Disease: Acute Chest Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TNFSF11 O14788 TNF superfamily member 11 Signaling 4.9E-03 0.453 0.846
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TGFB3 P10600 transforming growth factor beta 3 Signaling 0.99 0.498 0.808
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
SELPLG Q14242 selectin P ligand 0.18 0.564 0.692
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
PTX3 P26022 pentraxin 3 7.0E-05 0.457 0.808
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
MYDGF Q969H8 myeloid derived growth factor 3.5E-06 0.451 0.846
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MIR21 microRNA 21 0.363 0.846
MIR155 microRNA 155 0.384 0.885